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G0327 Colon ca scrn;bld-bsd biomrk

What G0327 is

Colorectal cancer screening; blood-based biomarker

HCPCS Level II long description, CMS October 2026 file. See the G codes page for the full section.

Medicare payment for G0327 (CY2026)

This code has no Physician Fee Schedule rate: Statutory exclusion - not payable under the Physician Fee Schedule. It may be paid under a different fee schedule (clinical laboratory, DMEPOS, anesthesia) or not paid at all - check the relevant CMS schedule.

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Medically Unlikely Edit (MUE)

Medicare caps G0327 at 1 unit per date of service for practitioner claims (MAI 2 - date of service edit (absolute): units above the MUE never pay), rationale: Code Descriptor / CPT Instruction. Units above the cap are denied unless the edit's adjudication rules allow an appeal with documentation.

Billed with G0327? These codes are bundled into it

G0327 is a Column 1 code in 145 active NCCI PTP edits. When one of these Column 2 codes is reported on the same date of service, it is denied as bundled - unless the edit's modifier indicator is 1 and documentation supports a distinct service with an NCCI-associated modifier.

Column 2 codeShort descriptionModifier indicator
0009U1 - modifier may bypassCheck pair
0068U1 - modifier may bypassCheck pair
0086U1 - modifier may bypassCheck pair
0091U0 - no modifier bypassCheck pair
0112U1 - modifier may bypassCheck pair
0115U1 - modifier may bypassCheck pair
0140U1 - modifier may bypassCheck pair
0141U1 - modifier may bypassCheck pair
0142U1 - modifier may bypassCheck pair
0163U0 - no modifier bypassCheck pair
0202U1 - modifier may bypassCheck pair
0321U1 - modifier may bypassCheck pair
0330U1 - modifier may bypassCheck pair
0424U1 - modifier may bypassCheck pair
0429U1 - modifier may bypassCheck pair
80503Path clin consltj sf 5-201 - modifier may bypassCheck pair
80504Path clin consltj mod 21-401 - modifier may bypassCheck pair
80505Path clin consltj high 41-601 - modifier may bypassCheck pair
80506Path clin consltj prolng svc1 - modifier may bypassCheck pair
81327Sept9 gen prmtr mthyltn alys0 - no modifier bypassCheck pair
81513Nfct ds bv rna vag flu alg1 - modifier may bypassCheck pair
84311Spectrophotometry1 - modifier may bypassCheck pair
86581Strptcs pneum antb serot ia1 - modifier may bypassCheck pair
87140Culture type immunofluoresc1 - modifier may bypassCheck pair
87143Culture typing glc/hplc1 - modifier may bypassCheck pair
87147Culture type immunologic1 - modifier may bypassCheck pair
87149Dna/rna direct probe1 - modifier may bypassCheck pair
87150Dna/rna amplified probe1 - modifier may bypassCheck pair
87152Culture type pulse field gel1 - modifier may bypassCheck pair
87153Dna/rna sequencing1 - modifier may bypassCheck pair

Showing 30 of 145 column 2 codes. Use the pair checker for any specific combination.

G0327 is bundled into these codes

G0327 appears as a Column 2 code in 174 active edits. Reported with one of these Column 1 codes on the same date of service, G0327 is the code that denies.

Column 1 codeShort descriptionModifier indicator
0001U1Check pair
0004M1Check pair
0005U1Check pair
0006M1Check pair
0007M1Check pair
0008U1Check pair
0010U1Check pair
0011M1Check pair
0012M1Check pair
0013M1Check pair
0016M1Check pair
0018U1Check pair
0019U1Check pair
0022U1Check pair
0023U1Check pair

Data: CMS CY2026 Physician Fee Schedule RVU file (October release, RVU26D) and Medicare NCCI PTP practitioner edits v32.3 (2026 Q4). Verify against the official files before billing or contracting decisions.