G0327 Colon ca scrn;bld-bsd biomrk
What G0327 is
Colorectal cancer screening; blood-based biomarker
HCPCS Level II long description, CMS October 2026 file. See the G codes page for the full section.
Medicare payment for G0327 (CY2026)
This code has no Physician Fee Schedule rate: Statutory exclusion - not payable under the Physician Fee Schedule. It may be paid under a different fee schedule (clinical laboratory, DMEPOS, anesthesia) or not paid at all - check the relevant CMS schedule.
Medically Unlikely Edit (MUE)
Medicare caps G0327 at 1 unit per date of service for practitioner claims (MAI 2 - date of service edit (absolute): units above the MUE never pay), rationale: Code Descriptor / CPT Instruction. Units above the cap are denied unless the edit's adjudication rules allow an appeal with documentation.
Billed with G0327? These codes are bundled into it
G0327 is a Column 1 code in 145 active NCCI PTP edits. When one of these Column 2 codes is reported on the same date of service, it is denied as bundled - unless the edit's modifier indicator is 1 and documentation supports a distinct service with an NCCI-associated modifier.
| Column 2 code | Short description | Modifier indicator | |
|---|---|---|---|
0009U | 1 - modifier may bypass | Check pair | |
0068U | 1 - modifier may bypass | Check pair | |
0086U | 1 - modifier may bypass | Check pair | |
0091U | 0 - no modifier bypass | Check pair | |
0112U | 1 - modifier may bypass | Check pair | |
0115U | 1 - modifier may bypass | Check pair | |
0140U | 1 - modifier may bypass | Check pair | |
0141U | 1 - modifier may bypass | Check pair | |
0142U | 1 - modifier may bypass | Check pair | |
0163U | 0 - no modifier bypass | Check pair | |
0202U | 1 - modifier may bypass | Check pair | |
0321U | 1 - modifier may bypass | Check pair | |
0330U | 1 - modifier may bypass | Check pair | |
0424U | 1 - modifier may bypass | Check pair | |
0429U | 1 - modifier may bypass | Check pair | |
80503 | Path clin consltj sf 5-20 | 1 - modifier may bypass | Check pair |
80504 | Path clin consltj mod 21-40 | 1 - modifier may bypass | Check pair |
80505 | Path clin consltj high 41-60 | 1 - modifier may bypass | Check pair |
80506 | Path clin consltj prolng svc | 1 - modifier may bypass | Check pair |
81327 | Sept9 gen prmtr mthyltn alys | 0 - no modifier bypass | Check pair |
81513 | Nfct ds bv rna vag flu alg | 1 - modifier may bypass | Check pair |
84311 | Spectrophotometry | 1 - modifier may bypass | Check pair |
86581 | Strptcs pneum antb serot ia | 1 - modifier may bypass | Check pair |
87140 | Culture type immunofluoresc | 1 - modifier may bypass | Check pair |
87143 | Culture typing glc/hplc | 1 - modifier may bypass | Check pair |
87147 | Culture type immunologic | 1 - modifier may bypass | Check pair |
87149 | Dna/rna direct probe | 1 - modifier may bypass | Check pair |
87150 | Dna/rna amplified probe | 1 - modifier may bypass | Check pair |
87152 | Culture type pulse field gel | 1 - modifier may bypass | Check pair |
87153 | Dna/rna sequencing | 1 - modifier may bypass | Check pair |
Showing 30 of 145 column 2 codes. Use the pair checker for any specific combination.
G0327 is bundled into these codes
G0327 appears as a Column 2 code in 174 active edits. Reported with one of these Column 1 codes on the same date of service, G0327 is the code that denies.
| Column 1 code | Short description | Modifier indicator | |
|---|---|---|---|
0001U | 1 | Check pair | |
0004M | 1 | Check pair | |
0005U | 1 | Check pair | |
0006M | 1 | Check pair | |
0007M | 1 | Check pair | |
0008U | 1 | Check pair | |
0010U | 1 | Check pair | |
0011M | 1 | Check pair | |
0012M | 1 | Check pair | |
0013M | 1 | Check pair | |
0016M | 1 | Check pair | |
0018U | 1 | Check pair | |
0019U | 1 | Check pair | |
0022U | 1 | Check pair | |
0023U | 1 | Check pair |
Data: CMS CY2026 Physician Fee Schedule RVU file (October release, RVU26D) and Medicare NCCI PTP practitioner edits v32.3 (2026 Q4). Verify against the official files before billing or contracting decisions.