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E0781

What E0781 is

Ambulatory infusion pump, single or multiple channels, electric or battery operated, with administrative equipment, worn by patient

HCPCS Level II long description, CMS October 2026 file. See the E codes page for the full section.

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Medically Unlikely Edit (MUE)

Medicare caps E0781 at 1 unit per date of service for practitioner claims (MAI 2 - date of service edit (absolute): units above the MUE never pay), rationale: Code Descriptor / CPT Instruction. Units above the cap are denied unless the edit's adjudication rules allow an appeal with documentation.

Billed with E0781? These codes are bundled into it

E0781 is a Column 1 code in 1 active NCCI PTP edits. When one of these Column 2 codes is reported on the same date of service, it is denied as bundled - unless the edit's modifier indicator is 1 and documentation supports a distinct service with an NCCI-associated modifier.

Column 2 codeShort descriptionModifier indicator
E07821 - modifier may bypassCheck pair

E0781 is bundled into these codes

E0781 appears as a Column 2 code in 13 active edits. Reported with one of these Column 1 codes on the same date of service, E0781 is the code that denies.

Column 1 codeShort descriptionModifier indicator
96360Hydration iv infusion init1Check pair
96361Hydrate iv infusion add-on1Check pair
96365Ther/proph/diag iv inf init1Check pair
96366Ther/proph/diag iv inf addon1Check pair
96367Tx/proph/dg addl seq iv inf1Check pair
96369Sc ther infusion up to 1 hr1Check pair
96370Sc ther infusion addl hr1Check pair
96371Sc ther infusion reset pump1Check pair
96413Chemo iv infusion 1 hr1Check pair
96422Chemo ia infusion up to 1 hr1Check pair
96440Chmotx admn plrl cav thrcnts1Check pair
96446Chemotx admn pertl cav impl1Check pair
M0224Pemivibart infusion1Check pair

Data: CMS CY2026 Physician Fee Schedule RVU file (October release, RVU26D) and Medicare NCCI PTP practitioner edits v32.3 (2026 Q4). Verify against the official files before billing or contracting decisions.