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C2616

What C2616 is

Brachytherapy source, non-stranded, yttrium-90, per source

HCPCS Level II long description, CMS October 2026 file. See the C codes page for the full section.

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Medically Unlikely Edit (MUE)

Medicare caps C2616 at 1 unit per date of service for practitioner claims (MAI 3 - date of service edit (clinical): units above the MUE may pay with documentation on appeal), rationale: Clinical: Data. Units above the cap are denied unless the edit's adjudication rules allow an appeal with documentation.

C2616 is bundled into these codes

C2616 appears as a Column 2 code in 22 active edits. Reported with one of these Column 1 codes on the same date of service, C2616 is the code that denies.

Column 1 codeShort descriptionModifier indicator
78201Liver imaging static only1Check pair
78202Liver imaging with vasc flow1Check pair
78215Lvr&spleen img static only1Check pair
78216Lvr&spleen img w/vasc flow1Check pair
78291Pertl-ven shunt patency test1Check pair
78300Bone imaging limited area1Check pair
78305Bone imaging multiple areas1Check pair
78306Bone imaging whole body1Check pair
78315Bone imaging 3 phase1Check pair
78445Vascular flow imaging1Check pair
78580Lung perfusion imaging1Check pair
78582Lung ventilat&perfus imaging1Check pair
78800Rp loclzj tum 1 area 1 d img1Check pair
78801Rp loclzj tum 2+area 1+d img1Check pair
78802Rp loclzj tum whbdy 1 d img1Check pair

Data: CMS CY2026 Physician Fee Schedule RVU file (October release, RVU26D) and Medicare NCCI PTP practitioner edits v32.3 (2026 Q4). Verify against the official files before billing or contracting decisions.