96425 Chemotherapy infusion method
What 96425 is
CMS fee schedule short descriptor: Chemotherapy infusion method.
Full CPT long descriptions are licensed by the American Medical Association and are not published on this site; the short descriptor above is the one CMS prints in its own fee schedule file. See About CPT.
Medicare payment for 96425 (CY2026)
| Work RVU | Practice expense RVU | Malpractice RVU | Total | Medicare rate | |
|---|---|---|---|---|---|
| Non-facility (office) | 0.17 | 4.93 | 0.11 | 5.21 | $174.02 |
| Facility (hospital, ASC) | 0.17 | 4.93 | 0.11 | 5.21 | $174.02 |
National rates: total RVUs x the CY2026 conversion factor of 33.4009 (non-QP), before geographic adjustment. Actual Medicare payment is 80% of the rate shown after the deductible; the patient or secondary payer owes the 20% coinsurance.
Status: Active - payable under the Physician Fee Schedule. Global period: Global concept does not apply.
Medically Unlikely Edit (MUE)
Medicare caps 96425 at 1 unit per date of service for practitioner claims (MAI 3 - date of service edit (clinical): units above the MUE may pay with documentation on appeal), rationale: Nature of Service/Procedure. Units above the cap are denied unless the edit's adjudication rules allow an appeal with documentation.
Billed with 96425? These codes are bundled into it
96425 is a Column 1 code in 43 active NCCI PTP edits. When one of these Column 2 codes is reported on the same date of service, it is denied as bundled - unless the edit's modifier indicator is 1 and documentation supports a distinct service with an NCCI-associated modifier.
| Column 2 code | Short description | Modifier indicator | |
|---|---|---|---|
0708T | Id ca immntx prep & 1st njx | 1 - modifier may bypass | Check pair |
0709T | Id ca immntx each addl njx | 1 - modifier may bypass | Check pair |
11900 | Inject skin lesions </w 7 | 1 - modifier may bypass | Check pair |
11901 | Inject skin lesions >7 | 1 - modifier may bypass | Check pair |
36500 | Insertion of catheter vein | 1 - modifier may bypass | Check pair |
36591 | Draw blood off venous device | 0 - no modifier bypass | Check pair |
36592 | Collect blood from picc | 0 - no modifier bypass | Check pair |
64450 | Njx aa&/strd other pn/branch | 1 - modifier may bypass | Check pair |
64454 | Njx aa&/strd gnclr nrv brnch | 1 - modifier may bypass | Check pair |
64473 | Lwr xtr fscl pln blk uni njx | 1 - modifier may bypass | Check pair |
64474 | Lwr xtr fscl pln blk uni nfs | 1 - modifier may bypass | Check pair |
64486 | Tap block unil by injection | 1 - modifier may bypass | Check pair |
64487 | Tap block uni by infusion | 1 - modifier may bypass | Check pair |
64488 | Tap block bi injection | 1 - modifier may bypass | Check pair |
64489 | Tap block bi by infusion | 1 - modifier may bypass | Check pair |
75893 | Venous sampling by catheter | 1 - modifier may bypass | Check pair |
96360 | Hydration iv infusion init | 1 - modifier may bypass | Check pair |
96365 | Ther/proph/diag iv inf init | 1 - modifier may bypass | Check pair |
96372 | Ther/proph/diag inj sc/im | 1 - modifier may bypass | Check pair |
96374 | Ther/proph/diag inj iv push | 1 - modifier may bypass | Check pair |
96375 | Tx/pro/dx inj new drug addon | 1 - modifier may bypass | Check pair |
96376 | Tx/pro/dx inj same drug adon | 1 - modifier may bypass | Check pair |
96377 | Applicaton on-body injector | 1 - modifier may bypass | Check pair |
96521 | Refill/maint portable pump | 0 - no modifier bypass | Check pair |
96522 | Refill/maint pump/resvr syst | 0 - no modifier bypass | Check pair |
96523 | Irrig drug delivery device | 0 - no modifier bypass | Check pair |
99202 | Office o/p new sf 15 min | 1 - modifier may bypass | Check pair |
99203 | Office o/p new low 30 min | 1 - modifier may bypass | Check pair |
99204 | Office o/p new mod 45 min | 1 - modifier may bypass | Check pair |
99205 | Office o/p new hi 60 min | 1 - modifier may bypass | Check pair |
Showing 30 of 43 column 2 codes. Use the pair checker for any specific combination.
96425 is bundled into these codes
96425 appears as a Column 2 code in 69 active edits. Reported with one of these Column 1 codes on the same date of service, 96425 is the code that denies.
| Column 1 code | Short description | Modifier indicator | |
|---|---|---|---|
36823 | Insertion of cannula(s) | 1 | Check pair |
61650 | Evasc prlng admn rx agnt 1st | 1 | Check pair |
61651 | Evasc prlng admn rx agnt add | 1 | Check pair |
77750 | Infuse radioactive materials | 0 | Check pair |
99221 | 1st hosp ip/obs sf/low 40 | 1 | Check pair |
99222 | 1st hosp ip/obs moderate 55 | 1 | Check pair |
99223 | 1st hosp ip/obs high 75 | 1 | Check pair |
99231 | Sbsq hosp ip/obs sf/low 25 | 0 | Check pair |
99232 | Sbsq hosp ip/obs moderate 35 | 0 | Check pair |
99233 | Sbsq hosp ip/obs high 50 | 0 | Check pair |
99234 | Hosp ip/obs sm dt sf/low 45 | 1 | Check pair |
99235 | Hosp ip/obs same date mod 70 | 1 | Check pair |
99236 | Hosp ip/obs same date hi 85 | 1 | Check pair |
99238 | Hosp ip/obs dschrg mgmt 30/< | 1 | Check pair |
99239 | Hosp ip/obs dschrg mgmt >30 | 1 | Check pair |
Data: CMS CY2026 Physician Fee Schedule RVU file (October release, RVU26D) and Medicare NCCI PTP practitioner edits v32.3 (2026 Q4). Verify against the official files before billing or contracting decisions.