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88160 Cytopath smear other source

What 88160 is

CMS fee schedule short descriptor: Cytopath smear other source.

Full CPT long descriptions are licensed by the American Medical Association and are not published on this site; the short descriptor above is the one CMS prints in its own fee schedule file. See About CPT.

Medicare payment for 88160 (CY2026)

Work RVUPractice expense RVUMalpractice RVUTotalMedicare rate
Non-facility (office)0.491.920.032.44$81.50
Facility (hospital, ASC)0.491.920.032.44$81.50

National rates: total RVUs x the CY2026 conversion factor of 33.4009 (non-QP), before geographic adjustment. Actual Medicare payment is 80% of the rate shown after the deductible; the patient or secondary payer owes the 20% coinsurance.


Status: Active - payable under the Physician Fee Schedule. Global period: Global concept does not apply.

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Medically Unlikely Edit (MUE)

Medicare caps 88160 at 4 units per date of service for practitioner claims (MAI 3 - date of service edit (clinical): units above the MUE may pay with documentation on appeal), rationale: Clinical: Data. Units above the cap are denied unless the edit's adjudication rules allow an appeal with documentation.

Billed with 88160? These codes are bundled into it

88160 is a Column 1 code in 6 active NCCI PTP edits. When one of these Column 2 codes is reported on the same date of service, it is denied as bundled - unless the edit's modifier indicator is 1 and documentation supports a distinct service with an NCCI-associated modifier.

Column 2 codeShort descriptionModifier indicator
88104Cytopath fl nongyn smears1 - modifier may bypassCheck pair
88106Cytopath fl nongyn filter1 - modifier may bypassCheck pair
88108Cytopath concentrate tech1 - modifier may bypassCheck pair
88173Cytopath eval fna report1 - modifier may bypassCheck pair
88387Macroscopic xm dsj&prep tiss1 - modifier may bypassCheck pair
96523Irrig drug delivery device0 - no modifier bypassCheck pair

88160 is bundled into these codes

88160 appears as a Column 2 code in 24 active edits. Reported with one of these Column 1 codes on the same date of service, 88160 is the code that denies.

Column 1 codeShort descriptionModifier indicator
0018M1Check pair
81560Trnsplj pd lvr&bwl cd154+cll1Check pair
88112Cytopath cell enhance tech1Check pair
88150Cytopath c/v manual1Check pair
88161Cytopath smear other source0Check pair
88162Cytopath smear other source1Check pair
88164Cytopath tbs c/v manual1Check pair
88184Flowcytometry/ tc 1 marker1Check pair
88187Flowcytometry/read 2-81Check pair
88188Flowcytometry/read 9-151Check pair
88189Flowcytometry/read 16 & >1Check pair
88304Tissue exam by pathologist1Check pair
88305Tissue exam by pathologist1Check pair
88307Tissue exam by pathologist1Check pair
88309Tissue exam by pathologist1Check pair

Data: CMS CY2026 Physician Fee Schedule RVU file (October release, RVU26D) and Medicare NCCI PTP practitioner edits v32.3 (2026 Q4). Verify against the official files before billing or contracting decisions.