87253 Virus inoculate tissue addl
What 87253 is
CMS fee schedule short descriptor: Virus inoculate tissue addl.
Full CPT long descriptions are licensed by the American Medical Association and are not published on this site; the short descriptor above is the one CMS prints in its own fee schedule file. See About CPT.
Medicare payment for 87253 (CY2026)
This code has no Physician Fee Schedule rate: Statutory exclusion - not payable under the Physician Fee Schedule. It may be paid under a different fee schedule (clinical laboratory, DMEPOS, anesthesia) or not paid at all - check the relevant CMS schedule.
Medically Unlikely Edit (MUE)
Medicare caps 87253 at 2 units per date of service for practitioner claims (MAI 3 - date of service edit (clinical): units above the MUE may pay with documentation on appeal), rationale: Clinical: Data. Units above the cap are denied unless the edit's adjudication rules allow an appeal with documentation.
Billed with 87253? These codes are bundled into it
87253 is a Column 1 code in 57 active NCCI PTP edits. When one of these Column 2 codes is reported on the same date of service, it is denied as bundled - unless the edit's modifier indicator is 1 and documentation supports a distinct service with an NCCI-associated modifier.
| Column 2 code | Short description | Modifier indicator | |
|---|---|---|---|
0429U | 1 - modifier may bypass | Check pair | |
0463U | 1 - modifier may bypass | Check pair | |
87260 | Adenovirus ag if | 1 - modifier may bypass | Check pair |
87267 | Enterovirus antibody dfa | 1 - modifier may bypass | Check pair |
87271 | Cytomegalovirus dfa | 1 - modifier may bypass | Check pair |
87274 | Herpes simplex 1 ag if | 1 - modifier may bypass | Check pair |
87276 | Influenza a ag if | 1 - modifier may bypass | Check pair |
87280 | Respiratory syncytial ag if | 1 - modifier may bypass | Check pair |
87290 | Varicella zoster ag if | 1 - modifier may bypass | Check pair |
87301 | Adenovirus ag ia | 1 - modifier may bypass | Check pair |
87305 | Aspergillus ag ia | 1 - modifier may bypass | Check pair |
87332 | Cytomegalovirus ag ia | 1 - modifier may bypass | Check pair |
87340 | Hepatitis b surface ag ia | 1 - modifier may bypass | Check pair |
87350 | Hepatitis be ag ia | 1 - modifier may bypass | Check pair |
87380 | Hepatitis delta agent ag ia | 1 - modifier may bypass | Check pair |
87389 | Hiv-1 ag w/hiv-1&-2 ab ag ia | 1 - modifier may bypass | Check pair |
87390 | Hiv-1 ag ia | 1 - modifier may bypass | Check pair |
87391 | Hiv-2 ag ia | 1 - modifier may bypass | Check pair |
87420 | Resp syncytial virus ag ia | 1 - modifier may bypass | Check pair |
87425 | Rotavirus ag ia | 1 - modifier may bypass | Check pair |
87467 | Hepatitis b surface ag quan | 1 - modifier may bypass | Check pair |
87483 | Cns dna amp probe type 12-25 | 1 - modifier may bypass | Check pair |
87495 | Cytomeg dna dir probe | 1 - modifier may bypass | Check pair |
87496 | Cytomeg dna amp probe | 1 - modifier may bypass | Check pair |
87497 | Cytomeg dna quant | 1 - modifier may bypass | Check pair |
87498 | Enterovirus probe&revrs trns | 1 - modifier may bypass | Check pair |
87516 | Hepatitis b dna amp probe | 1 - modifier may bypass | Check pair |
87517 | Hepatitis b dna quant | 1 - modifier may bypass | Check pair |
87520 | Hepatitis c rna dir probe | 1 - modifier may bypass | Check pair |
87521 | Hepatitis c probe&rvrs trnsc | 1 - modifier may bypass | Check pair |
Showing 30 of 57 column 2 codes. Use the pair checker for any specific combination.
87253 is bundled into these codes
87253 appears as a Column 2 code in 11 active edits. Reported with one of these Column 1 codes on the same date of service, 87253 is the code that denies.
| Column 1 code | Short description | Modifier indicator | |
|---|---|---|---|
0202U | 1 | Check pair | |
0502U | 1 | Check pair | |
0527U | 1 | Check pair | |
87254 | Virus inoculation shell via | 1 | Check pair |
87255 | Genet virus isolate hsv | 1 | Check pair |
87500 | Vanomycin dna amp probe | 1 | Check pair |
87501 | Influenza dna amp prob 1+ | 1 | Check pair |
87502 | Influenza dna amp probe | 1 | Check pair |
87626 | Hpv sep hi-rsk typ&pool rslt | 1 | Check pair |
87636 | Sarscov2 & inf a&b amp prb | 1 | Check pair |
87637 | Sarscov2&inf a&b&rsv amp prb | 1 | Check pair |
Data: CMS CY2026 Physician Fee Schedule RVU file (October release, RVU26D) and Medicare NCCI PTP practitioner edits v32.3 (2026 Q4). Verify against the official files before billing or contracting decisions.