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86581 Strptcs pneum antb serot ia

What 86581 is

CMS fee schedule short descriptor: Strptcs pneum antb serot ia.

Full CPT long descriptions are licensed by the American Medical Association and are not published on this site; the short descriptor above is the one CMS prints in its own fee schedule file. See About CPT.

Medicare payment for 86581 (CY2026)

This code has no Physician Fee Schedule rate: Statutory exclusion - not payable under the Physician Fee Schedule. It may be paid under a different fee schedule (clinical laboratory, DMEPOS, anesthesia) or not paid at all - check the relevant CMS schedule.

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Medically Unlikely Edit (MUE)

Medicare caps 86581 at 1 unit per date of service for practitioner claims (MAI 2 - date of service edit (absolute): units above the MUE never pay), rationale: CMS Policy. Units above the cap are denied unless the edit's adjudication rules allow an appeal with documentation.

Billed with 86581? These codes are bundled into it

86581 is a Column 1 code in 6 active NCCI PTP edits. When one of these Column 2 codes is reported on the same date of service, it is denied as bundled - unless the edit's modifier indicator is 1 and documentation supports a distinct service with an NCCI-associated modifier.

Column 2 codeShort descriptionModifier indicator
36591Draw blood off venous device0 - no modifier bypassCheck pair
36592Collect blood from picc0 - no modifier bypassCheck pair
80503Path clin consltj sf 5-201 - modifier may bypassCheck pair
80504Path clin consltj mod 21-401 - modifier may bypassCheck pair
80505Path clin consltj high 41-601 - modifier may bypassCheck pair
96523Irrig drug delivery device0 - no modifier bypassCheck pair

86581 is bundled into these codes

86581 appears as a Column 2 code in 8 active edits. Reported with one of these Column 1 codes on the same date of service, 86581 is the code that denies.

Column 1 codeShort descriptionModifier indicator
86317Immunoassay infectious agent1Check pair
86318Ia infectious agent antibody1Check pair
87149Dna/rna direct probe1Check pair
87150Dna/rna amplified probe1Check pair
87153Dna/rna sequencing1Check pair
87154Cul typ id bld pthgn 6+ trgt1Check pair
87801Detect agnt mult dna ampli1Check pair
G0327Colon ca scrn;bld-bsd biomrk1Check pair

Data: CMS CY2026 Physician Fee Schedule RVU file (October release, RVU26D) and Medicare NCCI PTP practitioner edits v32.3 (2026 Q4). Verify against the official files before billing or contracting decisions.