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86316 Immunoassay tumor other

What 86316 is

CMS fee schedule short descriptor: Immunoassay tumor other.

Full CPT long descriptions are licensed by the American Medical Association and are not published on this site; the short descriptor above is the one CMS prints in its own fee schedule file. See About CPT.

Medicare payment for 86316 (CY2026)

This code has no Physician Fee Schedule rate: Statutory exclusion - not payable under the Physician Fee Schedule. It may be paid under a different fee schedule (clinical laboratory, DMEPOS, anesthesia) or not paid at all - check the relevant CMS schedule.

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Medically Unlikely Edit (MUE)

Medicare caps 86316 at 2 units per date of service for practitioner claims (MAI 3 - date of service edit (clinical): units above the MUE may pay with documentation on appeal), rationale: Clinical: Data. Units above the cap are denied unless the edit's adjudication rules allow an appeal with documentation.

Billed with 86316? These codes are bundled into it

86316 is a Column 1 code in 2 active NCCI PTP edits. When one of these Column 2 codes is reported on the same date of service, it is denied as bundled - unless the edit's modifier indicator is 1 and documentation supports a distinct service with an NCCI-associated modifier.

Column 2 codeShort descriptionModifier indicator
86294Immunoassay tumor qual1 - modifier may bypassCheck pair
96523Irrig drug delivery device0 - no modifier bypassCheck pair

86316 is bundled into these codes

86316 appears as a Column 2 code in 9 active edits. Reported with one of these Column 1 codes on the same date of service, 86316 is the code that denies.

Column 1 codeShort descriptionModifier indicator
0021U1Check pair
0405U1Check pair
0433U1Check pair
0495U1Check pair
83950Oncoprotein her-2/neu1Check pair
83951Oncoprotein dcp1Check pair
86300Immunoassay tumor ca 15-31Check pair
86301Immunoassay tumor ca 19-91Check pair
86304Immunoassay tumor ca 1251Check pair

Data: CMS CY2026 Physician Fee Schedule RVU file (October release, RVU26D) and Medicare NCCI PTP practitioner edits v32.3 (2026 Q4). Verify against the official files before billing or contracting decisions.