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81546 Onc thyr mrna 10,196 gen alg

What 81546 is

CMS fee schedule short descriptor: Onc thyr mrna 10,196 gen alg.

Full CPT long descriptions are licensed by the American Medical Association and are not published on this site; the short descriptor above is the one CMS prints in its own fee schedule file. See About CPT.

Medicare payment for 81546 (CY2026)

This code has no Physician Fee Schedule rate: Statutory exclusion - not payable under the Physician Fee Schedule. It may be paid under a different fee schedule (clinical laboratory, DMEPOS, anesthesia) or not paid at all - check the relevant CMS schedule.

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Medically Unlikely Edit (MUE)

Medicare caps 81546 at 2 units per date of service for practitioner claims (MAI 3 - date of service edit (clinical): units above the MUE may pay with documentation on appeal), rationale: Nature of Service/Procedure. Units above the cap are denied unless the edit's adjudication rules allow an appeal with documentation.

Billed with 81546? These codes are bundled into it

81546 is a Column 1 code in 252 active NCCI PTP edits. When one of these Column 2 codes is reported on the same date of service, it is denied as bundled - unless the edit's modifier indicator is 1 and documentation supports a distinct service with an NCCI-associated modifier.

Column 2 codeShort descriptionModifier indicator
0009U1 - modifier may bypassCheck pair
0016U1 - modifier may bypassCheck pair
0017U1 - modifier may bypassCheck pair
0018U0 - no modifier bypassCheck pair
0026U0 - no modifier bypassCheck pair
0027U1 - modifier may bypassCheck pair
0030U1 - modifier may bypassCheck pair
0034U1 - modifier may bypassCheck pair
0040U1 - modifier may bypassCheck pair
0046U1 - modifier may bypassCheck pair
0049U1 - modifier may bypassCheck pair
0070U1 - modifier may bypassCheck pair
0086U1 - modifier may bypassCheck pair
0111U1 - modifier may bypassCheck pair
0136U1 - modifier may bypassCheck pair
0137U1 - modifier may bypassCheck pair
0138U1 - modifier may bypassCheck pair
0229U1 - modifier may bypassCheck pair
0230U1 - modifier may bypassCheck pair
0231U1 - modifier may bypassCheck pair
0233U1 - modifier may bypassCheck pair
0234U1 - modifier may bypassCheck pair
0235U1 - modifier may bypassCheck pair
0236U1 - modifier may bypassCheck pair
0252U1 - modifier may bypassCheck pair
0286U1 - modifier may bypassCheck pair
0313U0 - no modifier bypassCheck pair
0317U1 - modifier may bypassCheck pair
0318U1 - modifier may bypassCheck pair
0341U1 - modifier may bypassCheck pair

Showing 30 of 252 column 2 codes. Use the pair checker for any specific combination.

81546 is bundled into these codes

81546 appears as a Column 2 code in 55 active edits. Reported with one of these Column 1 codes on the same date of service, 81546 is the code that denies.

Column 1 codeShort descriptionModifier indicator
0060U1Check pair
0102U1Check pair
0103U1Check pair
0129U1Check pair
0130U1Check pair
0133U1Check pair
0134U1Check pair
0232U1Check pair
0237U1Check pair
0238U1Check pair
0239U1Check pair
0242U1Check pair
0244U1Check pair
0253U1Check pair
0287U1Check pair

Data: CMS CY2026 Physician Fee Schedule RVU file (October release, RVU26D) and Medicare NCCI PTP practitioner edits v32.3 (2026 Q4). Verify against the official files before billing or contracting decisions.