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81535 Oncology gynecologic

What 81535 is

CMS fee schedule short descriptor: Oncology gynecologic.

Full CPT long descriptions are licensed by the American Medical Association and are not published on this site; the short descriptor above is the one CMS prints in its own fee schedule file. See About CPT.

Medicare payment for 81535 (CY2026)

This code has no Physician Fee Schedule rate: Statutory exclusion - not payable under the Physician Fee Schedule. It may be paid under a different fee schedule (clinical laboratory, DMEPOS, anesthesia) or not paid at all - check the relevant CMS schedule.

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Medically Unlikely Edit (MUE)

Medicare caps 81535 at 1 unit per date of service for practitioner claims (MAI 2 - date of service edit (absolute): units above the MUE never pay), rationale: Code Descriptor / CPT Instruction. Units above the cap are denied unless the edit's adjudication rules allow an appeal with documentation.

Billed with 81535? These codes are bundled into it

81535 is a Column 1 code in 21 active NCCI PTP edits. When one of these Column 2 codes is reported on the same date of service, it is denied as bundled - unless the edit's modifier indicator is 1 and documentation supports a distinct service with an NCCI-associated modifier.

Column 2 codeShort descriptionModifier indicator
0156U1 - modifier may bypassCheck pair
0212U1 - modifier may bypassCheck pair
0213U1 - modifier may bypassCheck pair
0318U1 - modifier may bypassCheck pair
0336U1 - modifier may bypassCheck pair
80503Path clin consltj sf 5-201 - modifier may bypassCheck pair
80504Path clin consltj mod 21-401 - modifier may bypassCheck pair
80505Path clin consltj high 41-601 - modifier may bypassCheck pair
80506Path clin consltj prolng svc1 - modifier may bypassCheck pair
81228Cytog alys chrml abnr cgh1 - modifier may bypassCheck pair
81229Cytog alys chrml abnr snpcgh1 - modifier may bypassCheck pair
88230Tissue culture lymphocyte1 - modifier may bypassCheck pair
88233Tissue culture skin/biopsy1 - modifier may bypassCheck pair
88235Tissue culture placenta1 - modifier may bypassCheck pair
88237Tissue culture bone marrow1 - modifier may bypassCheck pair
88239Tissue culture tumor1 - modifier may bypassCheck pair
88271Cytogenetics dna probe1 - modifier may bypassCheck pair
88291Cyto/molecular report1 - modifier may bypassCheck pair
88313Special stains group 21 - modifier may bypassCheck pair
96523Irrig drug delivery device0 - no modifier bypassCheck pair
G0452Molecular pathology interpr1 - modifier may bypassCheck pair

81535 is bundled into these codes

81535 appears as a Column 2 code in 3 active edits. Reported with one of these Column 1 codes on the same date of service, 81535 is the code that denies.

Column 1 codeShort descriptionModifier indicator
0425U1Check pair
0435U1Check pair
81195Cytog genom-wid alys hem mal1Check pair

Data: CMS CY2026 Physician Fee Schedule RVU file (October release, RVU26D) and Medicare NCCI PTP practitioner edits v32.3 (2026 Q4). Verify against the official files before billing or contracting decisions.