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81519 Oncology breast mrna

What 81519 is

CMS fee schedule short descriptor: Oncology breast mrna.

Full CPT long descriptions are licensed by the American Medical Association and are not published on this site; the short descriptor above is the one CMS prints in its own fee schedule file. See About CPT.

Medicare payment for 81519 (CY2026)

This code has no Physician Fee Schedule rate: Statutory exclusion - not payable under the Physician Fee Schedule. It may be paid under a different fee schedule (clinical laboratory, DMEPOS, anesthesia) or not paid at all - check the relevant CMS schedule.

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Medically Unlikely Edit (MUE)

Medicare caps 81519 at 1 unit per date of service for practitioner claims (MAI 2 - date of service edit (absolute): units above the MUE never pay), rationale: Code Descriptor / CPT Instruction. Units above the cap are denied unless the edit's adjudication rules allow an appeal with documentation.

Billed with 81519? These codes are bundled into it

81519 is a Column 1 code in 288 active NCCI PTP edits. When one of these Column 2 codes is reported on the same date of service, it is denied as bundled - unless the edit's modifier indicator is 1 and documentation supports a distinct service with an NCCI-associated modifier.

Column 2 codeShort descriptionModifier indicator
0009U1 - modifier may bypassCheck pair
0016U1 - modifier may bypassCheck pair
0017U1 - modifier may bypassCheck pair
0027U1 - modifier may bypassCheck pair
0030U1 - modifier may bypassCheck pair
0034U1 - modifier may bypassCheck pair
0040U1 - modifier may bypassCheck pair
0045U0 - no modifier bypassCheck pair
0046U1 - modifier may bypassCheck pair
0049U1 - modifier may bypassCheck pair
0070U1 - modifier may bypassCheck pair
0071U1 - modifier may bypassCheck pair
0086U1 - modifier may bypassCheck pair
0111U1 - modifier may bypassCheck pair
0136U1 - modifier may bypassCheck pair
0137U1 - modifier may bypassCheck pair
0138U1 - modifier may bypassCheck pair
0140U1 - modifier may bypassCheck pair
0141U1 - modifier may bypassCheck pair
0142U1 - modifier may bypassCheck pair
0155U1 - modifier may bypassCheck pair
0156U1 - modifier may bypassCheck pair
0157U1 - modifier may bypassCheck pair
0158U1 - modifier may bypassCheck pair
0159U1 - modifier may bypassCheck pair
0160U1 - modifier may bypassCheck pair
0161U1 - modifier may bypassCheck pair
0169U1 - modifier may bypassCheck pair
0177U1 - modifier may bypassCheck pair
0212U1 - modifier may bypassCheck pair

Showing 30 of 288 column 2 codes. Use the pair checker for any specific combination.

81519 is bundled into these codes

81519 appears as a Column 2 code in 60 active edits. Reported with one of these Column 1 codes on the same date of service, 81519 is the code that denies.

Column 1 codeShort descriptionModifier indicator
0060U1Check pair
0101U1Check pair
0102U1Check pair
0103U1Check pair
0129U1Check pair
0130U1Check pair
0133U1Check pair
0134U1Check pair
0162U1Check pair
0171U1Check pair
0232U1Check pair
0237U1Check pair
0238U1Check pair
0239U1Check pair
0242U1Check pair

Data: CMS CY2026 Physician Fee Schedule RVU file (October release, RVU26D) and Medicare NCCI PTP practitioner edits v32.3 (2026 Q4). Verify against the official files before billing or contracting decisions.