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81506 Endo assay seven anal

What 81506 is

CMS fee schedule short descriptor: Endo assay seven anal.

Full CPT long descriptions are licensed by the American Medical Association and are not published on this site; the short descriptor above is the one CMS prints in its own fee schedule file. See About CPT.

Medicare payment for 81506 (CY2026)

This code has no Physician Fee Schedule rate: Statutory exclusion - not payable under the Physician Fee Schedule. It may be paid under a different fee schedule (clinical laboratory, DMEPOS, anesthesia) or not paid at all - check the relevant CMS schedule.

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Medically Unlikely Edit (MUE)

Medicare caps 81506 at 1 unit per date of service for practitioner claims (MAI 2 - date of service edit (absolute): units above the MUE never pay), rationale: Code Descriptor / CPT Instruction. Units above the cap are denied unless the edit's adjudication rules allow an appeal with documentation.

Billed with 81506? These codes are bundled into it

81506 is a Column 1 code in 12 active NCCI PTP edits. When one of these Column 2 codes is reported on the same date of service, it is denied as bundled - unless the edit's modifier indicator is 1 and documentation supports a distinct service with an NCCI-associated modifier.

Column 2 codeShort descriptionModifier indicator
80503Path clin consltj sf 5-201 - modifier may bypassCheck pair
80504Path clin consltj mod 21-401 - modifier may bypassCheck pair
80505Path clin consltj high 41-601 - modifier may bypassCheck pair
80506Path clin consltj prolng svc1 - modifier may bypassCheck pair
82728Assay of ferritin0 - no modifier bypassCheck pair
82947Assay glucose blood quant0 - no modifier bypassCheck pair
83036Hemoglobin glycosylated a1c0 - no modifier bypassCheck pair
83525Assay of insulin0 - no modifier bypassCheck pair
86141C-reactive protein hs0 - no modifier bypassCheck pair
88291Cyto/molecular report1 - modifier may bypassCheck pair
96523Irrig drug delivery device0 - no modifier bypassCheck pair
G0452Molecular pathology interpr1 - modifier may bypassCheck pair

Data: CMS CY2026 Physician Fee Schedule RVU file (October release, RVU26D) and Medicare NCCI PTP practitioner edits v32.3 (2026 Q4). Verify against the official files before billing or contracting decisions.