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81503 Onco (ovar) five proteins

What 81503 is

CMS fee schedule short descriptor: Onco (ovar) five proteins.

Full CPT long descriptions are licensed by the American Medical Association and are not published on this site; the short descriptor above is the one CMS prints in its own fee schedule file. See About CPT.

Medicare payment for 81503 (CY2026)

This code has no Physician Fee Schedule rate: Statutory exclusion - not payable under the Physician Fee Schedule. It may be paid under a different fee schedule (clinical laboratory, DMEPOS, anesthesia) or not paid at all - check the relevant CMS schedule.

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Medically Unlikely Edit (MUE)

Medicare caps 81503 at 1 unit per date of service for practitioner claims (MAI 2 - date of service edit (absolute): units above the MUE never pay), rationale: Code Descriptor / CPT Instruction. Units above the cap are denied unless the edit's adjudication rules allow an appeal with documentation.

Billed with 81503? These codes are bundled into it

81503 is a Column 1 code in 14 active NCCI PTP edits. When one of these Column 2 codes is reported on the same date of service, it is denied as bundled - unless the edit's modifier indicator is 1 and documentation supports a distinct service with an NCCI-associated modifier.

Column 2 codeShort descriptionModifier indicator
0251U0 - no modifier bypassCheck pair
80503Path clin consltj sf 5-201 - modifier may bypassCheck pair
80504Path clin consltj mod 21-401 - modifier may bypassCheck pair
80505Path clin consltj high 41-601 - modifier may bypassCheck pair
80506Path clin consltj prolng svc1 - modifier may bypassCheck pair
82172Assay of apolipoprotein0 - no modifier bypassCheck pair
82232Assay of beta-2 protein0 - no modifier bypassCheck pair
83695Assay of lipoprotein(a)1 - modifier may bypassCheck pair
84134Assay of prealbumin0 - no modifier bypassCheck pair
84466Assay of transferrin0 - no modifier bypassCheck pair
86304Immunoassay tumor ca 1250 - no modifier bypassCheck pair
88291Cyto/molecular report1 - modifier may bypassCheck pair
96523Irrig drug delivery device0 - no modifier bypassCheck pair
G0452Molecular pathology interpr1 - modifier may bypassCheck pair

81503 is bundled into these codes

81503 appears as a Column 2 code in 1 active edits. Reported with one of these Column 1 codes on the same date of service, 81503 is the code that denies.

Column 1 codeShort descriptionModifier indicator
0507U1Check pair

Data: CMS CY2026 Physician Fee Schedule RVU file (October release, RVU26D) and Medicare NCCI PTP practitioner edits v32.3 (2026 Q4). Verify against the official files before billing or contracting decisions.