81457 So neo gsap dna mcrstl ins
What 81457 is
CMS fee schedule short descriptor: So neo gsap dna mcrstl ins.
Full CPT long descriptions are licensed by the American Medical Association and are not published on this site; the short descriptor above is the one CMS prints in its own fee schedule file. See About CPT.
Medicare payment for 81457 (CY2026)
This code has no Physician Fee Schedule rate: Statutory exclusion - not payable under the Physician Fee Schedule. It may be paid under a different fee schedule (clinical laboratory, DMEPOS, anesthesia) or not paid at all - check the relevant CMS schedule.
Medically Unlikely Edit (MUE)
Medicare caps 81457 at 1 unit per date of service for practitioner claims (MAI 2 - date of service edit (absolute): units above the MUE never pay), rationale: Code Descriptor / CPT Instruction. Units above the cap are denied unless the edit's adjudication rules allow an appeal with documentation.
81457 is bundled into these codes
81457 appears as a Column 2 code in 10 active edits. Reported with one of these Column 1 codes on the same date of service, 81457 is the code that denies.
| Column 1 code | Short description | Modifier indicator | |
|---|---|---|---|
0422U | 1 | Check pair | |
0485U | 1 | Check pair | |
0486U | 0 | Check pair | |
0487U | 0 | Check pair | |
0491U | 1 | Check pair | |
0492U | 1 | Check pair | |
0523U | 1 | Check pair | |
0530U | 1 | Check pair | |
81458 | So gsap dna cpy nmbr&mcrstl | 0 | Check pair |
81459 | So neo gsap dna/dna&rna | 0 | Check pair |
Data: CMS CY2026 Physician Fee Schedule RVU file (October release, RVU26D) and Medicare NCCI PTP practitioner edits v32.3 (2026 Q4). Verify against the official files before billing or contracting decisions.