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81442 Noonan spectrum disorders

What 81442 is

CMS fee schedule short descriptor: Noonan spectrum disorders.

Full CPT long descriptions are licensed by the American Medical Association and are not published on this site; the short descriptor above is the one CMS prints in its own fee schedule file. See About CPT.

Medicare payment for 81442 (CY2026)

This code has no Physician Fee Schedule rate: Statutory exclusion - not payable under the Physician Fee Schedule. It may be paid under a different fee schedule (clinical laboratory, DMEPOS, anesthesia) or not paid at all - check the relevant CMS schedule.

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Medically Unlikely Edit (MUE)

Medicare caps 81442 at 1 unit per date of service for practitioner claims (MAI 2 - date of service edit (absolute): units above the MUE never pay), rationale: Code Descriptor / CPT Instruction. Units above the cap are denied unless the edit's adjudication rules allow an appeal with documentation.

Billed with 81442? These codes are bundled into it

81442 is a Column 1 code in 323 active NCCI PTP edits. When one of these Column 2 codes is reported on the same date of service, it is denied as bundled - unless the edit's modifier indicator is 1 and documentation supports a distinct service with an NCCI-associated modifier.

Column 2 codeShort descriptionModifier indicator
0009U1 - modifier may bypassCheck pair
0016U1 - modifier may bypassCheck pair
0017U1 - modifier may bypassCheck pair
0027U1 - modifier may bypassCheck pair
0030U1 - modifier may bypassCheck pair
0034U1 - modifier may bypassCheck pair
0040U1 - modifier may bypassCheck pair
0045U1 - modifier may bypassCheck pair
0046U1 - modifier may bypassCheck pair
0047U1 - modifier may bypassCheck pair
0049U1 - modifier may bypassCheck pair
0055U1 - modifier may bypassCheck pair
0069U1 - modifier may bypassCheck pair
0070U1 - modifier may bypassCheck pair
0071U1 - modifier may bypassCheck pair
0086U1 - modifier may bypassCheck pair
0087U1 - modifier may bypassCheck pair
0088U1 - modifier may bypassCheck pair
0089U1 - modifier may bypassCheck pair
0090U1 - modifier may bypassCheck pair
0108U1 - modifier may bypassCheck pair
0111U1 - modifier may bypassCheck pair
0118U1 - modifier may bypassCheck pair
0133U1 - modifier may bypassCheck pair
0136U1 - modifier may bypassCheck pair
0137U1 - modifier may bypassCheck pair
0138U1 - modifier may bypassCheck pair
0140U1 - modifier may bypassCheck pair
0141U1 - modifier may bypassCheck pair
0142U1 - modifier may bypassCheck pair

Showing 30 of 323 column 2 codes. Use the pair checker for any specific combination.

81442 is bundled into these codes

81442 appears as a Column 2 code in 9 active edits. Reported with one of these Column 1 codes on the same date of service, 81442 is the code that denies.

Column 1 codeShort descriptionModifier indicator
0156U1Check pair
0212U1Check pair
0213U1Check pair
0318U1Check pair
0336U1Check pair
0425U1Check pair
81228Cytog alys chrml abnr cgh1Check pair
81229Cytog alys chrml abnr snpcgh1Check pair
81349Cytog alys chrml abnr lw-ps1Check pair

Data: CMS CY2026 Physician Fee Schedule RVU file (October release, RVU26D) and Medicare NCCI PTP practitioner edits v32.3 (2026 Q4). Verify against the official files before billing or contracting decisions.