81442 Noonan spectrum disorders
What 81442 is
CMS fee schedule short descriptor: Noonan spectrum disorders.
Full CPT long descriptions are licensed by the American Medical Association and are not published on this site; the short descriptor above is the one CMS prints in its own fee schedule file. See About CPT.
Medicare payment for 81442 (CY2026)
This code has no Physician Fee Schedule rate: Statutory exclusion - not payable under the Physician Fee Schedule. It may be paid under a different fee schedule (clinical laboratory, DMEPOS, anesthesia) or not paid at all - check the relevant CMS schedule.
Medically Unlikely Edit (MUE)
Medicare caps 81442 at 1 unit per date of service for practitioner claims (MAI 2 - date of service edit (absolute): units above the MUE never pay), rationale: Code Descriptor / CPT Instruction. Units above the cap are denied unless the edit's adjudication rules allow an appeal with documentation.
Billed with 81442? These codes are bundled into it
81442 is a Column 1 code in 323 active NCCI PTP edits. When one of these Column 2 codes is reported on the same date of service, it is denied as bundled - unless the edit's modifier indicator is 1 and documentation supports a distinct service with an NCCI-associated modifier.
| Column 2 code | Short description | Modifier indicator | |
|---|---|---|---|
0009U | 1 - modifier may bypass | Check pair | |
0016U | 1 - modifier may bypass | Check pair | |
0017U | 1 - modifier may bypass | Check pair | |
0027U | 1 - modifier may bypass | Check pair | |
0030U | 1 - modifier may bypass | Check pair | |
0034U | 1 - modifier may bypass | Check pair | |
0040U | 1 - modifier may bypass | Check pair | |
0045U | 1 - modifier may bypass | Check pair | |
0046U | 1 - modifier may bypass | Check pair | |
0047U | 1 - modifier may bypass | Check pair | |
0049U | 1 - modifier may bypass | Check pair | |
0055U | 1 - modifier may bypass | Check pair | |
0069U | 1 - modifier may bypass | Check pair | |
0070U | 1 - modifier may bypass | Check pair | |
0071U | 1 - modifier may bypass | Check pair | |
0086U | 1 - modifier may bypass | Check pair | |
0087U | 1 - modifier may bypass | Check pair | |
0088U | 1 - modifier may bypass | Check pair | |
0089U | 1 - modifier may bypass | Check pair | |
0090U | 1 - modifier may bypass | Check pair | |
0108U | 1 - modifier may bypass | Check pair | |
0111U | 1 - modifier may bypass | Check pair | |
0118U | 1 - modifier may bypass | Check pair | |
0133U | 1 - modifier may bypass | Check pair | |
0136U | 1 - modifier may bypass | Check pair | |
0137U | 1 - modifier may bypass | Check pair | |
0138U | 1 - modifier may bypass | Check pair | |
0140U | 1 - modifier may bypass | Check pair | |
0141U | 1 - modifier may bypass | Check pair | |
0142U | 1 - modifier may bypass | Check pair |
Showing 30 of 323 column 2 codes. Use the pair checker for any specific combination.
81442 is bundled into these codes
81442 appears as a Column 2 code in 9 active edits. Reported with one of these Column 1 codes on the same date of service, 81442 is the code that denies.
| Column 1 code | Short description | Modifier indicator | |
|---|---|---|---|
0156U | 1 | Check pair | |
0212U | 1 | Check pair | |
0213U | 1 | Check pair | |
0318U | 1 | Check pair | |
0336U | 1 | Check pair | |
0425U | 1 | Check pair | |
81228 | Cytog alys chrml abnr cgh | 1 | Check pair |
81229 | Cytog alys chrml abnr snpcgh | 1 | Check pair |
81349 | Cytog alys chrml abnr lw-ps | 1 | Check pair |
Data: CMS CY2026 Physician Fee Schedule RVU file (October release, RVU26D) and Medicare NCCI PTP practitioner edits v32.3 (2026 Q4). Verify against the official files before billing or contracting decisions.