81349 Cytog alys chrml abnr lw-ps
What 81349 is
CMS fee schedule short descriptor: Cytog alys chrml abnr lw-ps.
Full CPT long descriptions are licensed by the American Medical Association and are not published on this site; the short descriptor above is the one CMS prints in its own fee schedule file. See About CPT.
Medicare payment for 81349 (CY2026)
This code has no Physician Fee Schedule rate: Statutory exclusion - not payable under the Physician Fee Schedule. It may be paid under a different fee schedule (clinical laboratory, DMEPOS, anesthesia) or not paid at all - check the relevant CMS schedule.
Medically Unlikely Edit (MUE)
Medicare caps 81349 at 1 unit per date of service for practitioner claims (MAI 2 - date of service edit (absolute): units above the MUE never pay), rationale: Code Descriptor / CPT Instruction. Units above the cap are denied unless the edit's adjudication rules allow an appeal with documentation.
Billed with 81349? These codes are bundled into it
81349 is a Column 1 code in 166 active NCCI PTP edits. When one of these Column 2 codes is reported on the same date of service, it is denied as bundled - unless the edit's modifier indicator is 1 and documentation supports a distinct service with an NCCI-associated modifier.
| Column 2 code | Short description | Modifier indicator | |
|---|---|---|---|
0169U | 1 - modifier may bypass | Check pair | |
0171U | 1 - modifier may bypass | Check pair | |
0177U | 1 - modifier may bypass | Check pair | |
0202U | 1 - modifier may bypass | Check pair | |
0212U | 0 - no modifier bypass | Check pair | |
0213U | 0 - no modifier bypass | Check pair | |
0235U | 1 - modifier may bypass | Check pair | |
0330U | 1 - modifier may bypass | Check pair | |
0331U | 1 - modifier may bypass | Check pair | |
0336U | 0 - no modifier bypass | Check pair | |
0340U | 1 - modifier may bypass | Check pair | |
0405U | 1 - modifier may bypass | Check pair | |
0417U | 0 - no modifier bypass | Check pair | |
0425U | 0 - no modifier bypass | Check pair | |
0426U | 1 - modifier may bypass | Check pair | |
0429U | 1 - modifier may bypass | Check pair | |
0469U | 1 - modifier may bypass | Check pair | |
0489U | 1 - modifier may bypass | Check pair | |
81168 | Ccnd1/igh translocation alys | 1 - modifier may bypass | Check pair |
81410 | Aortic dysfunction/dilation | 1 - modifier may bypass | Check pair |
81411 | Aortic dysfunction/dilation | 1 - modifier may bypass | Check pair |
81412 | Ashkenazi jewish assoc dis | 1 - modifier may bypass | Check pair |
81415 | Exome sequence analysis | 1 - modifier may bypass | Check pair |
81416 | Exome sequence analysis | 1 - modifier may bypass | Check pair |
81417 | Exome re-evaluation | 1 - modifier may bypass | Check pair |
81420 | Fetal chrmoml aneuploidy | 1 - modifier may bypass | Check pair |
81425 | Genome sequence analysis | 1 - modifier may bypass | Check pair |
81426 | Genome sequence analysis | 1 - modifier may bypass | Check pair |
81427 | Genome re-evaluation | 1 - modifier may bypass | Check pair |
81430 | Hearing loss sequence analys | 1 - modifier may bypass | Check pair |
Showing 30 of 166 column 2 codes. Use the pair checker for any specific combination.
81349 is bundled into these codes
81349 appears as a Column 2 code in 12 active edits. Reported with one of these Column 1 codes on the same date of service, 81349 is the code that denies.
| Column 1 code | Short description | Modifier indicator | |
|---|---|---|---|
0010U | 1 | Check pair | |
0016M | 1 | Check pair | |
0079U | 0 | Check pair | |
0318U | 0 | Check pair | |
0413U | 1 | Check pair | |
0449U | 1 | Check pair | |
0454U | 1 | Check pair | |
0474U | 1 | Check pair | |
81195 | Cytog genom-wid alys hem mal | 1 | Check pair |
81228 | Cytog alys chrml abnr cgh | 0 | Check pair |
81229 | Cytog alys chrml abnr snpcgh | 0 | Check pair |
81546 | Onc thyr mrna 10,196 gen alg | 1 | Check pair |
Data: CMS CY2026 Physician Fee Schedule RVU file (October release, RVU26D) and Medicare NCCI PTP practitioner edits v32.3 (2026 Q4). Verify against the official files before billing or contracting decisions.