81258 Hba1/hba2 gene fam vrnt
What 81258 is
CMS fee schedule short descriptor: Hba1/hba2 gene fam vrnt.
Full CPT long descriptions are licensed by the American Medical Association and are not published on this site; the short descriptor above is the one CMS prints in its own fee schedule file. See About CPT.
Medicare payment for 81258 (CY2026)
This code has no Physician Fee Schedule rate: Statutory exclusion - not payable under the Physician Fee Schedule. It may be paid under a different fee schedule (clinical laboratory, DMEPOS, anesthesia) or not paid at all - check the relevant CMS schedule.
Medically Unlikely Edit (MUE)
Medicare caps 81258 at 1 unit per date of service for practitioner claims (MAI 2 - date of service edit (absolute): units above the MUE never pay), rationale: Code Descriptor / CPT Instruction. Units above the cap are denied unless the edit's adjudication rules allow an appeal with documentation.
Billed with 81258? These codes are bundled into it
81258 is a Column 1 code in 139 active NCCI PTP edits. When one of these Column 2 codes is reported on the same date of service, it is denied as bundled - unless the edit's modifier indicator is 1 and documentation supports a distinct service with an NCCI-associated modifier.
| Column 2 code | Short description | Modifier indicator | |
|---|---|---|---|
0009U | 1 - modifier may bypass | Check pair | |
0068U | 1 - modifier may bypass | Check pair | |
0086U | 1 - modifier may bypass | Check pair | |
0112U | 1 - modifier may bypass | Check pair | |
0115U | 1 - modifier may bypass | Check pair | |
0140U | 1 - modifier may bypass | Check pair | |
0141U | 1 - modifier may bypass | Check pair | |
0142U | 1 - modifier may bypass | Check pair | |
0202U | 1 - modifier may bypass | Check pair | |
0321U | 1 - modifier may bypass | Check pair | |
0330U | 1 - modifier may bypass | Check pair | |
0429U | 1 - modifier may bypass | Check pair | |
80503 | Path clin consltj sf 5-20 | 1 - modifier may bypass | Check pair |
80504 | Path clin consltj mod 21-40 | 1 - modifier may bypass | Check pair |
80505 | Path clin consltj high 41-60 | 1 - modifier may bypass | Check pair |
80506 | Path clin consltj prolng svc | 1 - modifier may bypass | Check pair |
81230 | Cyp3a4 gene common variants | 1 - modifier may bypass | Check pair |
81231 | Cyp3a5 gene common variants | 1 - modifier may bypass | Check pair |
81513 | Nfct ds bv rna vag flu alg | 1 - modifier may bypass | Check pair |
84311 | Spectrophotometry | 1 - modifier may bypass | Check pair |
87140 | Culture type immunofluoresc | 1 - modifier may bypass | Check pair |
87143 | Culture typing glc/hplc | 1 - modifier may bypass | Check pair |
87147 | Culture type immunologic | 1 - modifier may bypass | Check pair |
87149 | Dna/rna direct probe | 1 - modifier may bypass | Check pair |
87150 | Dna/rna amplified probe | 1 - modifier may bypass | Check pair |
87152 | Culture type pulse field gel | 1 - modifier may bypass | Check pair |
87153 | Dna/rna sequencing | 1 - modifier may bypass | Check pair |
87154 | Cul typ id bld pthgn 6+ trgt | 1 - modifier may bypass | Check pair |
87158 | Culture typing added method | 1 - modifier may bypass | Check pair |
87468 | Anaplsma phgcytophlm amp prb | 1 - modifier may bypass | Check pair |
Showing 30 of 139 column 2 codes. Use the pair checker for any specific combination.
81258 is bundled into these codes
81258 appears as a Column 2 code in 167 active edits. Reported with one of these Column 1 codes on the same date of service, 81258 is the code that denies.
| Column 1 code | Short description | Modifier indicator | |
|---|---|---|---|
0001U | 1 | Check pair | |
0004M | 1 | Check pair | |
0005U | 1 | Check pair | |
0006M | 1 | Check pair | |
0007M | 1 | Check pair | |
0008U | 1 | Check pair | |
0010U | 1 | Check pair | |
0011M | 1 | Check pair | |
0012M | 1 | Check pair | |
0013M | 1 | Check pair | |
0016M | 1 | Check pair | |
0018U | 1 | Check pair | |
0019U | 1 | Check pair | |
0022U | 1 | Check pair | |
0023U | 1 | Check pair |
Data: CMS CY2026 Physician Fee Schedule RVU file (October release, RVU26D) and Medicare NCCI PTP practitioner edits v32.3 (2026 Q4). Verify against the official files before billing or contracting decisions.