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80345 Drug screening barbiturates

What 80345 is

CMS fee schedule short descriptor: Drug screening barbiturates.

Full CPT long descriptions are licensed by the American Medical Association and are not published on this site; the short descriptor above is the one CMS prints in its own fee schedule file. See About CPT.

Medicare payment for 80345 (CY2026)

This code has no Physician Fee Schedule rate: Not valid for Medicare purposes. It may be paid under a different fee schedule (clinical laboratory, DMEPOS, anesthesia) or not paid at all - check the relevant CMS schedule.

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Medically Unlikely Edit (MUE)

Medicare caps 80345 at 1 unit per date of service for practitioner claims (MAI 3 - date of service edit (clinical): units above the MUE may pay with documentation on appeal), rationale: Code Descriptor / CPT Instruction. Units above the cap are denied unless the edit's adjudication rules allow an appeal with documentation.

Billed with 80345? These codes are bundled into it

80345 is a Column 1 code in 5 active NCCI PTP edits. When one of these Column 2 codes is reported on the same date of service, it is denied as bundled - unless the edit's modifier indicator is 1 and documentation supports a distinct service with an NCCI-associated modifier.

Column 2 codeShort descriptionModifier indicator
80503Path clin consltj sf 5-201 - modifier may bypassCheck pair
80504Path clin consltj mod 21-401 - modifier may bypassCheck pair
80505Path clin consltj high 41-601 - modifier may bypassCheck pair
80506Path clin consltj prolng svc1 - modifier may bypassCheck pair
96523Irrig drug delivery device0 - no modifier bypassCheck pair

80345 is bundled into these codes

80345 appears as a Column 2 code in 18 active edits. Reported with one of these Column 1 codes on the same date of service, 80345 is the code that denies.

Column 1 codeShort descriptionModifier indicator
0007U0Check pair
0011U0Check pair
0051U0Check pair
0054U0Check pair
0082U0Check pair
0093U0Check pair
0110U0Check pair
0116U0Check pair
0328U0Check pair
0517U1Check pair
0518U0Check pair
0519U0Check pair
0520U1Check pair
G0480Drug test def 1-7 classes0Check pair
G0481Drug test def 8-14 classes0Check pair

Data: CMS CY2026 Physician Fee Schedule RVU file (October release, RVU26D) and Medicare NCCI PTP practitioner edits v32.3 (2026 Q4). Verify against the official files before billing or contracting decisions.