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80305 Drug test prsmv dir opt obs

What 80305 is

CMS fee schedule short descriptor: Drug test prsmv dir opt obs.

Full CPT long descriptions are licensed by the American Medical Association and are not published on this site; the short descriptor above is the one CMS prints in its own fee schedule file. See About CPT.

Medicare payment for 80305 (CY2026)

This code has no Physician Fee Schedule rate: Statutory exclusion - not payable under the Physician Fee Schedule. It may be paid under a different fee schedule (clinical laboratory, DMEPOS, anesthesia) or not paid at all - check the relevant CMS schedule.

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Medically Unlikely Edit (MUE)

Medicare caps 80305 at 1 unit per date of service for practitioner claims (MAI 2 - date of service edit (absolute): units above the MUE never pay), rationale: Code Descriptor / CPT Instruction. Units above the cap are denied unless the edit's adjudication rules allow an appeal with documentation.

Billed with 80305? These codes are bundled into it

80305 is a Column 1 code in 22 active NCCI PTP edits. When one of these Column 2 codes is reported on the same date of service, it is denied as bundled - unless the edit's modifier indicator is 1 and documentation supports a distinct service with an NCCI-associated modifier.

Column 2 codeShort descriptionModifier indicator
0119U1 - modifier may bypassCheck pair
0251U1 - modifier may bypassCheck pair
80503Path clin consltj sf 5-201 - modifier may bypassCheck pair
80504Path clin consltj mod 21-401 - modifier may bypassCheck pair
80505Path clin consltj high 41-601 - modifier may bypassCheck pair
80506Path clin consltj prolng svc1 - modifier may bypassCheck pair
81000Urinalysis nonauto w/scope1 - modifier may bypassCheck pair
81001Urinalysis auto w/scope1 - modifier may bypassCheck pair
81002Urinalysis nonauto w/o scope1 - modifier may bypassCheck pair
81003Urinalysis auto w/o scope1 - modifier may bypassCheck pair
81005Urinalysis1 - modifier may bypassCheck pair
82542Col chromotography qual/quan1 - modifier may bypassCheck pair
82570Assay of urine creatinine1 - modifier may bypassCheck pair
83516Immunoassay nonantibody1 - modifier may bypassCheck pair
83518Immunoassay dipstick1 - modifier may bypassCheck pair
83519Ria nonantibody1 - modifier may bypassCheck pair
83520Immunoassay quant nos nonab1 - modifier may bypassCheck pair
83789Mass spectrometry qual/quan1 - modifier may bypassCheck pair
83986Assay ph body fluid nos1 - modifier may bypassCheck pair
84156Assay of protein urine1 - modifier may bypassCheck pair
84311Spectrophotometry1 - modifier may bypassCheck pair
96523Irrig drug delivery device0 - no modifier bypassCheck pair

80305 is bundled into these codes

80305 appears as a Column 2 code in 14 active edits. Reported with one of these Column 1 codes on the same date of service, 80305 is the code that denies.

Column 1 codeShort descriptionModifier indicator
0007U0Check pair
0051U1Check pair
0054U1Check pair
0082U1Check pair
0093U1Check pair
0110U1Check pair
0116U1Check pair
0227U0Check pair
0328U0Check pair
0457U1Check pair
0517U1Check pair
0520U1Check pair
80306Drug test prsmv instrmnt0Check pair
80307Drug test prsmv chem anlyzr0Check pair

Data: CMS CY2026 Physician Fee Schedule RVU file (October release, RVU26D) and Medicare NCCI PTP practitioner edits v32.3 (2026 Q4). Verify against the official files before billing or contracting decisions.