80053 Comprehen metabolic panel
What 80053 is
CMS fee schedule short descriptor: Comprehen metabolic panel.
Full CPT long descriptions are licensed by the American Medical Association and are not published on this site; the short descriptor above is the one CMS prints in its own fee schedule file. See About CPT.
Medicare payment for 80053 (CY2026)
This code has no Physician Fee Schedule rate: Statutory exclusion - not payable under the Physician Fee Schedule. It may be paid under a different fee schedule (clinical laboratory, DMEPOS, anesthesia) or not paid at all - check the relevant CMS schedule.
Medically Unlikely Edit (MUE)
Medicare caps 80053 at 1 unit per date of service for practitioner claims (MAI 3 - date of service edit (clinical): units above the MUE may pay with documentation on appeal), rationale: CMS Policy. Units above the cap are denied unless the edit's adjudication rules allow an appeal with documentation.
Billed with 80053? These codes are bundled into it
80053 is a Column 1 code in 20 active NCCI PTP edits. When one of these Column 2 codes is reported on the same date of service, it is denied as bundled - unless the edit's modifier indicator is 1 and documentation supports a distinct service with an NCCI-associated modifier.
| Column 2 code | Short description | Modifier indicator | |
|---|---|---|---|
80047 | Basic metablc pnl ionized ca | 1 - modifier may bypass | Check pair |
80048 | Basic metabolic pnl total ca | 0 - no modifier bypass | Check pair |
80051 | Electrolyte panel | 1 - modifier may bypass | Check pair |
80069 | Renal function panel | 0 - no modifier bypass | Check pair |
80076 | Hepatic function panel | 0 - no modifier bypass | Check pair |
82040 | Assay of serum albumin | 1 - modifier may bypass | Check pair |
82247 | Bilirubin total | 1 - modifier may bypass | Check pair |
82310 | Assay of calcium | 1 - modifier may bypass | Check pair |
82374 | Assay blood carbon dioxide | 1 - modifier may bypass | Check pair |
82435 | Assay of blood chloride | 1 - modifier may bypass | Check pair |
82565 | Assay of creatinine | 1 - modifier may bypass | Check pair |
82947 | Assay glucose blood quant | 1 - modifier may bypass | Check pair |
84075 | Assay alkaline phosphatase | 1 - modifier may bypass | Check pair |
84132 | Assay of serum potassium | 1 - modifier may bypass | Check pair |
84155 | Assay of protein serum | 1 - modifier may bypass | Check pair |
84295 | Assay of serum sodium | 1 - modifier may bypass | Check pair |
84450 | Transferase (ast) (sgot) | 1 - modifier may bypass | Check pair |
84460 | Alanine amino (alt) (sgpt) | 1 - modifier may bypass | Check pair |
84520 | Assay of urea nitrogen | 1 - modifier may bypass | Check pair |
96523 | Irrig drug delivery device | 0 - no modifier bypass | Check pair |
80053 is bundled into these codes
80053 appears as a Column 2 code in 4 active edits. Reported with one of these Column 1 codes on the same date of service, 80053 is the code that denies.
| Column 1 code | Short description | Modifier indicator | |
|---|---|---|---|
0002M | 0 | Check pair | |
0003M | 0 | Check pair | |
0166U | 0 | Check pair | |
0344U | 0 | Check pair |
Data: CMS CY2026 Physician Fee Schedule RVU file (October release, RVU26D) and Medicare NCCI PTP practitioner edits v32.3 (2026 Q4). Verify against the official files before billing or contracting decisions.