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43253 Egd us transmural injxn/mark

What 43253 is

CMS fee schedule short descriptor: Egd us transmural injxn/mark.

Full CPT long descriptions are licensed by the American Medical Association and are not published on this site; the short descriptor above is the one CMS prints in its own fee schedule file. See About CPT.

Medicare payment for 43253 (CY2026)

Work RVUPractice expense RVUMalpractice RVUTotalMedicare rate
Non-facility (office)4.611.780.506.89$230.13
Facility (hospital, ASC)4.611.780.506.89$230.13

National rates: total RVUs x the CY2026 conversion factor of 33.4009 (non-QP), before geographic adjustment. Actual Medicare payment is 80% of the rate shown after the deductible; the patient or secondary payer owes the 20% coinsurance.


Status: Active - payable under the Physician Fee Schedule. Global period: Global concept does not apply (endoscopic or minor procedure: global period is the day of the procedure).

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Medically Unlikely Edit (MUE)

Medicare caps 43253 at 1 unit per date of service for practitioner claims (MAI 3 - date of service edit (clinical): units above the MUE may pay with documentation on appeal), rationale: Nature of Service/Procedure. Units above the cap are denied unless the edit's adjudication rules allow an appeal with documentation.

Billed with 43253? These codes are bundled into it

43253 is a Column 1 code in 298 active NCCI PTP edits. When one of these Column 2 codes is reported on the same date of service, it is denied as bundled - unless the edit's modifier indicator is 1 and documentation supports a distinct service with an NCCI-associated modifier.

Column 2 codeShort descriptionModifier indicator
00520Anes closed chest px nos0 - no modifier bypassCheck pair
00731Anes upr gi ndsc px nos0 - no modifier bypassCheck pair
00732Anes upr gi ndsc px ercp0 - no modifier bypassCheck pair
00811Anes lwr intst ndsc nos0 - no modifier bypassCheck pair
00812Anes lwr intst scr colsc0 - no modifier bypassCheck pair
00813Anes upr lwr gi ndsc px0 - no modifier bypassCheck pair
0213TNjx paravert w/us cer/thor0 - no modifier bypassCheck pair
0216TNjx paravert w/us lumb/sac0 - no modifier bypassCheck pair
0596TTemp fml iu vlv-pmp 1st insj1 - modifier may bypassCheck pair
0597TTemp fml iu valve-pmp rplcmt1 - modifier may bypassCheck pair
0652TEgd flx transnasal dx br/wa0 - no modifier bypassCheck pair
0653TEgd flx transnasal bx 1/mlt1 - modifier may bypassCheck pair
0708TId ca immntx prep & 1st njx1 - modifier may bypassCheck pair
0709TId ca immntx each addl njx1 - modifier may bypassCheck pair
0903TEcg alg 12 lead reduced i&r1 - modifier may bypassCheck pair
0904TEcg alg 12 ld rdcd trcg only1 - modifier may bypassCheck pair
0905TEcg alg 12 ld rdcd i&r only1 - modifier may bypassCheck pair
10005Fna bx w/us gdn 1st les1 - modifier may bypassCheck pair
10007Fna bx w/fluor gdn 1st les1 - modifier may bypassCheck pair
10009Fna bx w/ct gdn 1st les1 - modifier may bypassCheck pair
10011Fna bx w/mr gdn 1st les1 - modifier may bypassCheck pair
10021Fna bx w/o img gdn 1st les1 - modifier may bypassCheck pair
12001Rpr s/n/ax/gen/trnk 2.5cm/<1 - modifier may bypassCheck pair
12002Rpr s/n/ax/gen/trnk2.6-7.5cm1 - modifier may bypassCheck pair
12004Rpr s/n/ax/gen/trk7.6-12.5cm1 - modifier may bypassCheck pair
12005Rpr s/n/a/gen/trk12.6-20.0cm1 - modifier may bypassCheck pair
12006Rpr s/n/a/gen/trk20.1-30.0cm1 - modifier may bypassCheck pair
12007Rpr s/n/ax/gen/trnk >30.0 cm1 - modifier may bypassCheck pair
12011Rpr f/e/e/n/l/m 2.5 cm/<1 - modifier may bypassCheck pair
12013Rpr f/e/e/n/l/m 2.6-5.0 cm1 - modifier may bypassCheck pair

Showing 30 of 298 column 2 codes. Use the pair checker for any specific combination.

43253 is bundled into these codes

43253 appears as a Column 2 code in 29 active edits. Reported with one of these Column 1 codes on the same date of service, 43253 is the code that denies.

Column 1 codeShort descriptionModifier indicator
0884TEsphgsc flx 1st tndsc dilat1Check pair
43240Egd w/transmural drain cyst0Check pair
43610Excision of stomach lesion1Check pair
43611Excision of stomach lesion1Check pair
43620Removal of stomach1Check pair
43621Removal of stomach1Check pair
43622Removal of stomach1Check pair
43631Removal of stomach partial1Check pair
43632Removal of stomach partial1Check pair
43633Removal of stomach partial1Check pair
43634Removal of stomach partial1Check pair
43635Removal of stomach partial1Check pair
43640Vagotomy & pylorus repair1Check pair
43641Vagotomy & pylorus repair1Check pair
43800Pyloroplasty1Check pair

Data: CMS CY2026 Physician Fee Schedule RVU file (October release, RVU26D) and Medicare NCCI PTP practitioner edits v32.3 (2026 Q4). Verify against the official files before billing or contracting decisions.