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0506U

What 0506U is

This code appears in the Medicare NCCI edit tables. It has no RVUs in the CY2026 Physician Fee Schedule file.

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Medically Unlikely Edit (MUE)

Medicare caps 0506U at 1 unit per date of service for practitioner claims (MAI 2 - date of service edit (absolute): units above the MUE never pay), rationale: Code Descriptor / CPT Instruction. Units above the cap are denied unless the edit's adjudication rules allow an appeal with documentation.

Billed with 0506U? These codes are bundled into it

0506U is a Column 1 code in 30 active NCCI PTP edits. When one of these Column 2 codes is reported on the same date of service, it is denied as bundled - unless the edit's modifier indicator is 1 and documentation supports a distinct service with an NCCI-associated modifier.

Column 2 codeShort descriptionModifier indicator
0114U0 - no modifier bypassCheck pair
0398U0 - no modifier bypassCheck pair
36591Draw blood off venous device0 - no modifier bypassCheck pair
36592Collect blood from picc0 - no modifier bypassCheck pair
80503Path clin consltj sf 5-201 - modifier may bypassCheck pair
80504Path clin consltj mod 21-401 - modifier may bypassCheck pair
80505Path clin consltj high 41-601 - modifier may bypassCheck pair
81228Cytog alys chrml abnr cgh1 - modifier may bypassCheck pair
81229Cytog alys chrml abnr snpcgh1 - modifier may bypassCheck pair
81400Mopath procedure level 11 - modifier may bypassCheck pair
81401Mopath procedure level 21 - modifier may bypassCheck pair
81402Mopath procedure level 31 - modifier may bypassCheck pair
81403Mopath procedure level 41 - modifier may bypassCheck pair
81404Mopath procedure level 51 - modifier may bypassCheck pair
81405Mopath procedure level 61 - modifier may bypassCheck pair
81406Mopath procedure level 71 - modifier may bypassCheck pair
81407Mopath procedure level 81 - modifier may bypassCheck pair
83789Mass spectrometry qual/quan1 - modifier may bypassCheck pair
84311Spectrophotometry1 - modifier may bypassCheck pair
88271Cytogenetics dna probe1 - modifier may bypassCheck pair
88272Cytogenetics 3-51 - modifier may bypassCheck pair
88273Cytogenetics 10-301 - modifier may bypassCheck pair
88274Cytogenetics 25-991 - modifier may bypassCheck pair
88275Cytogenetics 100-3001 - modifier may bypassCheck pair
88291Cyto/molecular report1 - modifier may bypassCheck pair
88365Insitu hybridization (fish)1 - modifier may bypassCheck pair
88366Insitu hybridization (fish)1 - modifier may bypassCheck pair
88367Insitu hybridization auto1 - modifier may bypassCheck pair
96523Irrig drug delivery device0 - no modifier bypassCheck pair
G0452Molecular pathology interpr1 - modifier may bypassCheck pair

0506U is bundled into these codes

0506U appears as a Column 2 code in 2 active edits. Reported with one of these Column 1 codes on the same date of service, 0506U is the code that denies.

Column 1 codeShort descriptionModifier indicator
0108U0Check pair
81408Mopath procedure level 91Check pair

Data: CMS CY2026 Physician Fee Schedule RVU file (October release, RVU26D) and Medicare NCCI PTP practitioner edits v32.3 (2026 Q4). Verify against the official files before billing or contracting decisions.