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0478U

What 0478U is

This code appears in the Medicare NCCI edit tables. It has no RVUs in the CY2026 Physician Fee Schedule file.

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Medically Unlikely Edit (MUE)

Medicare caps 0478U at 1 unit per date of service for practitioner claims (MAI 3 - date of service edit (clinical): units above the MUE may pay with documentation on appeal), rationale: Code Descriptor / CPT Instruction. Units above the cap are denied unless the edit's adjudication rules allow an appeal with documentation.

Billed with 0478U? These codes are bundled into it

0478U is a Column 1 code in 42 active NCCI PTP edits. When one of these Column 2 codes is reported on the same date of service, it is denied as bundled - unless the edit's modifier indicator is 1 and documentation supports a distinct service with an NCCI-associated modifier.

Column 2 codeShort descriptionModifier indicator
36591Draw blood off venous device0 - no modifier bypassCheck pair
36592Collect blood from picc0 - no modifier bypassCheck pair
80503Path clin consltj sf 5-201 - modifier may bypassCheck pair
80504Path clin consltj mod 21-401 - modifier may bypassCheck pair
80505Path clin consltj high 41-601 - modifier may bypassCheck pair
81191Ntrk1 translocation analysis1 - modifier may bypassCheck pair
81192Ntrk2 translocation analysis1 - modifier may bypassCheck pair
81193Ntrk3 translocation analysis1 - modifier may bypassCheck pair
81194Ntrk translocation analysis1 - modifier may bypassCheck pair
81232Dpyd gene common variants1 - modifier may bypassCheck pair
81235Egfr gene com variants1 - modifier may bypassCheck pair
81275Kras gene variants exon 21 - modifier may bypassCheck pair
81276Kras gene addl variants1 - modifier may bypassCheck pair
81346Tyms gene com variants1 - modifier may bypassCheck pair
81352Tp53 gene trgt sequence alys1 - modifier may bypassCheck pair
81353Tp53 gene known famil vrnt1 - modifier may bypassCheck pair
81400Mopath procedure level 11 - modifier may bypassCheck pair
81401Mopath procedure level 21 - modifier may bypassCheck pair
81402Mopath procedure level 31 - modifier may bypassCheck pair
81403Mopath procedure level 41 - modifier may bypassCheck pair
81404Mopath procedure level 51 - modifier may bypassCheck pair
81405Mopath procedure level 61 - modifier may bypassCheck pair
81406Mopath procedure level 71 - modifier may bypassCheck pair
81407Mopath procedure level 81 - modifier may bypassCheck pair
81408Mopath procedure level 91 - modifier may bypassCheck pair
81417Exome re-evaluation1 - modifier may bypassCheck pair
84311Spectrophotometry1 - modifier may bypassCheck pair
88271Cytogenetics dna probe1 - modifier may bypassCheck pair
88272Cytogenetics 3-51 - modifier may bypassCheck pair
88273Cytogenetics 10-301 - modifier may bypassCheck pair

Showing 30 of 42 column 2 codes. Use the pair checker for any specific combination.

0478U is bundled into these codes

0478U appears as a Column 2 code in 23 active edits. Reported with one of these Column 1 codes on the same date of service, 0478U is the code that denies.

Column 1 codeShort descriptionModifier indicator
0022U1Check pair
0080U0Check pair
0092U0Check pair
0179U1Check pair
0239U1Check pair
0242U1Check pair
0288U1Check pair
0317U0Check pair
0360U1Check pair
0388U1Check pair
0395U1Check pair
0406U0Check pair
0414U1Check pair
0499U1Check pair
0523U1Check pair

Data: CMS CY2026 Physician Fee Schedule RVU file (October release, RVU26D) and Medicare NCCI PTP practitioner edits v32.3 (2026 Q4). Verify against the official files before billing or contracting decisions.