0449U
What 0449U is
This code appears in the Medicare NCCI edit tables. It has no RVUs in the CY2026 Physician Fee Schedule file.
Medically Unlikely Edit (MUE)
Medicare caps 0449U at 1 unit per date of service for practitioner claims (MAI 2 - date of service edit (absolute): units above the MUE never pay), rationale: Code Descriptor / CPT Instruction. Units above the cap are denied unless the edit's adjudication rules allow an appeal with documentation.
Billed with 0449U? These codes are bundled into it
0449U is a Column 1 code in 50 active NCCI PTP edits. When one of these Column 2 codes is reported on the same date of service, it is denied as bundled - unless the edit's modifier indicator is 1 and documentation supports a distinct service with an NCCI-associated modifier.
| Column 2 code | Short description | Modifier indicator | |
|---|---|---|---|
0236U | 1 - modifier may bypass | Check pair | |
36591 | Draw blood off venous device | 0 - no modifier bypass | Check pair |
36592 | Collect blood from picc | 0 - no modifier bypass | Check pair |
80503 | Path clin consltj sf 5-20 | 1 - modifier may bypass | Check pair |
80504 | Path clin consltj mod 21-40 | 1 - modifier may bypass | Check pair |
80505 | Path clin consltj high 41-60 | 1 - modifier may bypass | Check pair |
81220 | Cftr gene com variants | 1 - modifier may bypass | Check pair |
81221 | Cftr gene known fam variants | 1 - modifier may bypass | Check pair |
81222 | Cftr gene dup/delet variants | 1 - modifier may bypass | Check pair |
81223 | Cftr gene full sequence | 1 - modifier may bypass | Check pair |
81224 | Cftr gene intron poly t | 1 - modifier may bypass | Check pair |
81228 | Cytog alys chrml abnr cgh | 1 - modifier may bypass | Check pair |
81229 | Cytog alys chrml abnr snpcgh | 1 - modifier may bypass | Check pair |
81257 | Hba1/hba2 gene | 1 - modifier may bypass | Check pair |
81258 | Hba1/hba2 gene fam vrnt | 1 - modifier may bypass | Check pair |
81259 | Hba1/hba2 full gene sequence | 1 - modifier may bypass | Check pair |
81269 | Hba1/hba2 gene dup/del vrnts | 1 - modifier may bypass | Check pair |
81329 | Smn1 gene dos/deletion alys | 1 - modifier may bypass | Check pair |
81336 | Smn1 gene full gene sequence | 1 - modifier may bypass | Check pair |
81337 | Smn1 gen nown famil seq vrnt | 1 - modifier may bypass | Check pair |
81349 | Cytog alys chrml abnr lw-ps | 1 - modifier may bypass | Check pair |
81361 | Hbb gene com variants | 1 - modifier may bypass | Check pair |
81362 | Hbb gene known fam variant | 1 - modifier may bypass | Check pair |
81363 | Hbb gene dup/del variants | 1 - modifier may bypass | Check pair |
81364 | Hbb full gene sequence | 1 - modifier may bypass | Check pair |
81400 | Mopath procedure level 1 | 1 - modifier may bypass | Check pair |
81401 | Mopath procedure level 2 | 1 - modifier may bypass | Check pair |
81402 | Mopath procedure level 3 | 1 - modifier may bypass | Check pair |
81403 | Mopath procedure level 4 | 1 - modifier may bypass | Check pair |
81404 | Mopath procedure level 5 | 1 - modifier may bypass | Check pair |
Showing 30 of 50 column 2 codes. Use the pair checker for any specific combination.
0449U is bundled into these codes
0449U appears as a Column 2 code in 6 active edits. Reported with one of these Column 1 codes on the same date of service, 0449U is the code that denies.
| Column 1 code | Short description | Modifier indicator | |
|---|---|---|---|
0336U | 1 | Check pair | |
0417U | 1 | Check pair | |
0425U | 1 | Check pair | |
81415 | Exome sequence analysis | 1 | Check pair |
81425 | Genome sequence analysis | 1 | Check pair |
81443 | Genetic tstg severe inh cond | 1 | Check pair |
Data: CMS CY2026 Physician Fee Schedule RVU file (October release, RVU26D) and Medicare NCCI PTP practitioner edits v32.3 (2026 Q4). Verify against the official files before billing or contracting decisions.