0335U
What 0335U is
This code appears in the Medicare NCCI edit tables. It has no RVUs in the CY2026 Physician Fee Schedule file.
Medically Unlikely Edit (MUE)
Medicare caps 0335U at 2 units per date of service for practitioner claims (MAI 3 - date of service edit (clinical): units above the MUE may pay with documentation on appeal), rationale: Clinical: CMS Workgroup. Units above the cap are denied unless the edit's adjudication rules allow an appeal with documentation.
Billed with 0335U? These codes are bundled into it
0335U is a Column 1 code in 16 active NCCI PTP edits. When one of these Column 2 codes is reported on the same date of service, it is denied as bundled - unless the edit's modifier indicator is 1 and documentation supports a distinct service with an NCCI-associated modifier.
| Column 2 code | Short description | Modifier indicator | |
|---|---|---|---|
0094U | 0 - no modifier bypass | Check pair | |
0252U | 0 - no modifier bypass | Check pair | |
0260U | 1 - modifier may bypass | Check pair | |
0265U | 1 - modifier may bypass | Check pair | |
0326U | 1 - modifier may bypass | Check pair | |
0341U | 0 - no modifier bypass | Check pair | |
0425U | 1 - modifier may bypass | Check pair | |
0454U | 0 - no modifier bypass | Check pair | |
0469U | 0 - no modifier bypass | Check pair | |
0489U | 1 - modifier may bypass | Check pair | |
81415 | Exome sequence analysis | 0 - no modifier bypass | Check pair |
81425 | Genome sequence analysis | 0 - no modifier bypass | Check pair |
81434 | Hered rta do gen seq 15 | 0 - no modifier bypass | Check pair |
81437 | Hered neuroend tum-rlt do 5+ | 0 - no modifier bypass | Check pair |
81443 | Genetic tstg severe inh cond | 0 - no modifier bypass | Check pair |
81448 | Hrdtry perph neurphy panel | 0 - no modifier bypass | Check pair |
Data: CMS CY2026 Physician Fee Schedule RVU file (October release, RVU26D) and Medicare NCCI PTP practitioner edits v32.3 (2026 Q4). Verify against the official files before billing or contracting decisions.